Clinical Trials Directory

Trials / Terminated

TerminatedNCT01351675

Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes

Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes: the Occurrence of Renal Events (BEACON)

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
2,185 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study assesses the efficacy of bardoxolone methyl relative to placebo in delaying progression to end-stage renal disease (ESRD) and cardiovascular deaths in patients with Stage 4 Chronic Kidney Disease (CKD) and type 2 diabetes receiving standard of care.

Conditions

Interventions

TypeNameDescription
DRUGPlaceboOral, once daily
DRUGBardoxolone Methyl: 20 mg20 mg, oral, once daily

Timeline

Start date
2011-06-30
Primary completion
2012-10-31
Completion
2012-12-31
First posted
2011-05-11
Last updated
2025-05-29

Source: ClinicalTrials.gov record NCT01351675. Inclusion in this directory is not an endorsement.

Bardoxolone Methyl Evaluation in Patients With Chronic Kidney Disease and Type 2 Diabetes (NCT01351675) · Clinical Trials Directory