Clinical Trials Directory

Trials / Completed

CompletedNCT01347346

Gene Therapy for WAS

Phase I/II Clinical Trial of Haematopoietic Stem Cell Gene Therapy for the Wiskott-Aldrich Syndrome

Status
Completed
Phase
Phase 1 / Phase 2
Study type
Interventional
Enrollment
5 (actual)
Sponsor
Genethon · Academic / Other
Sex
Male
Age
Healthy volunteers
Not accepted

Summary

This is a phase I/II study to evaluate the safety and efficacy of Hematopoietic Stem Cell genetherapy for the Wiskott-Aldrich Syndrome.

Detailed description

This clinical trial is an ex vivo gene therapy trial. The investigational product corresponds to autologous CD34+ cells transduced with a lentiviral vector harboring the human WASP gene.

Conditions

Interventions

TypeNameDescription
GENETICAutologous CD34 positive cells transduced with a lentiviral vector containing human WAS genetransplantation of patient's autologous CD34+ cells transduced with lentiviral vector containing human WAS gene

Timeline

Start date
2011-05-01
Primary completion
2016-01-13
Completion
2017-01-09
First posted
2011-05-04
Last updated
2018-05-22

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT01347346. Inclusion in this directory is not an endorsement.