NCT01311193

Circadian Sleep-wake Cycles and Light Therapy in Borderline Personality Disorder

Circadian Sleep-wake Cycles, Well-being and Light Therapy in Borderline Personality Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: —
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: —

Summary

Individuals with borderline personality disorder (BPD) frequently suffer from emotional instability, daytime fatigue and sleep disturbances. The investigators examined circadian rhythms, sleep and well-being in women with BPD under their habitual life conditions with and without light treatment. Treated women diagnosed with BPD were investigated during 3 weeks without and 3 weeks with morning LT. Rest-activity cycles were continuously measured using wrist actigraphy, together with proximal skin temperature. Saliva samples were collected weekly to determine the diurnal melatonin rhythm. A range of self-ratings and questionnaires were used to assess depression and clinical state throughout the 6-week protocol. Ten matched healthy women followed the same 6-week protocol without light treatment.

Conditions

• Borderline Personality Disorder
• Sleep Disturbances
• Depression

Interventions

Type	Name	Description
OTHER	light therapy	early morning exposures to bright light, 8000lux for 40min, daily during 3 weeks

Timeline

• First posted: 2011-03-09
• Last updated: 2011-03-09

Locations

1 site across 1 country: Switzerland