Clinical Trials Directory

Trials / Completed

CompletedNCT01299636

Study of PM060184 in Patients With Advanced Solid Tumors

Phase I, Multicenter, Open-label, Dose-escalating, Clinical and Pharmacokinetic Study of PM060184 Administered Intravenously to Patients With Advanced Solid Tumors

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
60 (actual)
Sponsor
PharmaMar · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of the study is to determine the maximum tolerated dose and the recommended dose and to evaluate the safety and tolerability of PM060184.

Detailed description

This trial intends to determine the maximum tolerated dose and the recommended dose, to evaluate the safety and tolerability, to determine the pharmacokinetics and to evaluate the antitumor activity of PM060184 in patients with advanced solid tumors.

Conditions

Interventions

TypeNameDescription
DRUGPM060184PM060184 administered intravenously (i.v.) over 10 minutes at a starting dose of 4 mg/m2/day on three consecutive days q2w (on Days 1-3 and 15-17) every 28 days.

Timeline

Start date
2011-01-01
Primary completion
2015-08-01
Completion
2015-08-01
First posted
2011-02-18
Last updated
2015-11-02

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01299636. Inclusion in this directory is not an endorsement.