Clinical Trials Directory

Trials / Completed

CompletedNCT01286779

BAX 326 (rFIX) Continuation Study

BAX 326 (Recombinant Factor IX): Evaluation of Safety, Immunogenicity, and Hemostatic Efficacy in Previously Treated Patients With Severe (FIX Level < 1%) or Moderately Severe (FIX Level <= 2%) Hemophilia B - A Continuation Study

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
117 (actual)
Sponsor
Baxalta now part of Shire · Industry
Sex
All
Age
65 Years
Healthy volunteers
Not accepted

Summary

The purpose of this BAX 326 Continuation Study is to further investigate incremental recovery over time, the hemostatic efficacy, the safety, immunogenicity, and health-related quality of life (HR QoL) of BAX 326 in previously treated patients (PTPs) with severe and moderately severe hemophilia B who participated in BAX 326 pivotal study 250901 or BAX 326 pediatric study 251101.

Conditions

Interventions

TypeNameDescription
BIOLOGICALBAX 326 (Recombinant factor IX)The treatment with BAX 326 will be at the discretion of the investigator and will consist of either twice weekly prophylactic treatment with 50 IU/kg, modified prophylaxis, or on-demand treatment.

Timeline

Start date
2011-04-12
Primary completion
2017-06-29
Completion
2017-06-29
First posted
2011-01-31
Last updated
2021-05-20
Results posted
2018-09-10

Locations

42 sites across 17 countries: Argentina, Brazil, Bulgaria, Chile, Colombia, Czechia, India, Ireland, Italy, Japan, Poland, Romania, Russia, Sweden, Taiwan, Ukraine, United Kingdom

Source: ClinicalTrials.gov record NCT01286779. Inclusion in this directory is not an endorsement.