Clinical Trials Directory

Trials / Completed

CompletedNCT01281618

Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus

Status
Completed
Phase
Study type
Observational
Enrollment
48 (actual)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine the association between acid reflux and cell changes in Barrett's esophagus. Specific aim 1: To test the hypothesis that controlled acid reflux is associated with lesser degree of stromal activation. Specific aim 2: To test the hypothesis that stromal fibroblast derived growth factors drive BE epithelial proliferation.

Conditions

Interventions

TypeNameDescription
PROCEDURE24 hour pH study and upper endoscopy (EGD)All subjects enrolled will undergo 24 hour pH followed by EGD.

Timeline

Start date
2008-10-01
Primary completion
2011-06-01
Completion
2011-06-01
First posted
2011-01-24
Last updated
2013-05-06

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01281618. Inclusion in this directory is not an endorsement.

Influence of Acid Reflux on Stromal Epithelial Interaction in Barrett's Esophagus (NCT01281618) · Clinical Trials Directory