NCT01281397

Bleeding Prediction in Patients Following Cardiac Surgery Using Whole Blood Aggregometry and Thromboelastometry

Bleeding Prediction in Patients Undergoing Cardiac Surgery Using Whole Blood Impedance Aggregometry and Rotational Thromboelastometry

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 148 (actual)
• Sponsor: University of Zagreb · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Use of whole blood impedance aggregometry and rotational thromboelastometry can reveal useful data about platelet function and viscoelastic properties of blood clot in patients undergoing cardiac surgery. The purpose of this study is to clarify whether it is possible to predict patients on excessive risk of perioperative bleeding using whole blood impedance aggregometry and rotational thromoelastometry. Antiplatelet therapy is the cornerstone in treatment of patients with coronary artery disease. Another research goal is to determine the degree of response to antiplatelet therapy before and after surgery and to investigate whether patients by level of response to antiplatelet therapy before surgery have a higher risk of perioperative bleeding.

Conditions

• Heart Disease
• Coronary Artery Disease
• Aortic Valve Disease
• Mitral Valve Disease

Timeline

• Start date: 2009-08-01
• Primary completion: 2011-01-01
• Completion: 2011-01-01
• First posted: 2011-01-21
• Last updated: 2014-12-03

Locations

1 site across 1 country: Croatia