Clinical Trials Directory

Trials / Completed

CompletedNCT01276223

Evaluation of Anti-Inflammatory Treatment in Dry Eye Patients

A Multi-Center, Randomized, Double-Masked Evaluation of Anti-Inflammatory Treatment in Patients With Dry Eye

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
722 (actual)
Sponsor
Alcon Research · Industry
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The purpose of this study was to determine if difluprednate ophthalmic emulsion is effective in reducing the ocular symptoms of dry eye disease, as measured by a global Visual Analog Scale (VAS) discomfort score.

Detailed description

Following Run-In, patients qualifying for treatment were randomized 1:1 to receive Durezol (experimental group) or Vehicle (control group) for 5 weeks.

Conditions

Interventions

TypeNameDescription
DRUGDifluprednate 0.05% ophthalmic emulsionTopical ocular steroid
OTHERDifluprednate vehicleInactive ingredients used as Run-In and placebo comparator

Timeline

Start date
2011-02-01
Primary completion
2012-01-01
Completion
2012-01-01
First posted
2011-01-13
Last updated
2013-03-11
Results posted
2013-03-11

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01276223. Inclusion in this directory is not an endorsement.