Trials / Completed
CompletedNCT01241890
Prevention of CF Exacerbation in Childhood: PREVEC Study
Prevention of CF Exacerbation in Childhood (PREVEC): Early Recognition of Inflammation by Non-invasive Biomarkers in Exhaled Breath (Condensate)
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 49 (actual)
- Sponsor
- Maastricht University Medical Center · Academic / Other
- Sex
- All
- Age
- 5 Years – 18 Years
- Healthy volunteers
- Not accepted
Summary
Pulmonary exacerbations of CF are an important cause for the experienced disability of patients, respiratory symptoms, and decreases in lungfunction, which require antibiotic therapy at home or in the hospital. Therefore, prevention of exacerbations in CF is important. The aim of this study was to assess the predictive properties of inflammatory markers in exhaled breath for pulmonary exacerbations in children with CF. In addition the reliability of home monitor assessments of symptoms and lungfunction was investigated.
Conditions
- Cystic Fibrosis
- Children
- Exhaled Breath Condensate
- Non-invasive Inflammatory Markers
- Volatile Organic Compounds
- Home Monitoring
- Quality of Life
Timeline
- Start date
- 2011-10-01
- Primary completion
- 2013-08-01
- Completion
- 2014-07-01
- First posted
- 2010-11-16
- Last updated
- 2015-07-17
Locations
3 sites across 1 country: Netherlands
Source: ClinicalTrials.gov record NCT01241890. Inclusion in this directory is not an endorsement.