NCT01239381

Individualized Stereotactic Body Radiotherapy of Liver Metastases

Phase II Study of Individualized Stereotactic Body Radiotherapy of Liver Metastases

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: Massachusetts General Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Stereotactic body radiation therapy (SBRT) is a technique that is used to deliver radiation, to sites in the body. All participants in this study will be treated with SBRT using proton beam radiation. Proton beam radiation uses tiny particles to deliver radiation to tumors. The purpose of this research study is to determine if SBRT with protons will prevent tumor growth and reduce the treatment side effects for liver metastases.

Detailed description

* Participants receiving SBRT with protons, will receive radiation treatment as an outpatient at the Francis H. Burr Proton Therapy Center at Massachusetts General Hospital. * Not everyone who participates in this study will be receiving the same dose of radiation. The dose received will be determined by the size and location of the tumor(s). * Participants will receive 2-3 SBRT treatments per week for two weeks. * During radiation therapy visits the following tests/procedures will be performed: vital signs, physical examination, routine blood tests, research blood tests, and radiation planning. * Follow-up assessments will be performed once at 9 weeks after study treatment, then at 6 months, 12 months, 18 months and 24 months after treatment.

Conditions

• Solid Tumor
• Liver Metastases

Interventions

Type	Name	Description
RADIATION	Stereotactic body radiotherapy-proton	Dose will be determined by the size and location of the tumor(s); 2-3 treatments per week for two weeks

Timeline

• Start date: 2010-10-05
• Primary completion: 2016-01-01
• Completion: 2017-09-01
• First posted: 2010-11-11
• Last updated: 2025-09-30
• Results posted: 2017-07-13

Locations

2 sites across 1 country: United States