NCT01235715

The Use of Evicel to Reduce Blood Loss in Total Knee Replacement Surgery

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Hospital for Special Surgery, New York · Academic / Other
• Sex: All
• Age: 20 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Application of "Evicel" hemostatic matrix during operation for unilateral total knee replacement surgery (TKA) will result in decreased bleeding and postoperative drain output, a reduction in transfusion requirements, and less reduction of hemoglobin.

Detailed description

No additional data desired

Conditions

• Osteoarthritis

Interventions

Type	Name	Description
DRUG	Evicel fibrin sealant	Used for hemostasis to control bleeding. It has been shown to stop bleeding in 2 minutes or less. It is a combination of a biologic activated component containing human fibrinogen and topical thrombin functioning on wet, actively bleeding tissue.

Timeline

• Start date: 2010-09-01
• Primary completion: 2012-03-01
• Completion: 2012-09-01
• First posted: 2010-11-05
• Last updated: 2013-10-29
• Results posted: 2013-10-29

Locations

1 site across 1 country: United States