NCT01225484

Perioperative Analgesia After Knee Arthroplasty

Perioperative Analgetic Therapy After Knee Arthroplasty

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 123 (estimated)
• Sponsor: Landeskrankenhaus Feldbach · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare two accepted methods of pain control in knee arthroplasty surgery.The first method combines the periarticular injection of ropivacaine with continuous blockade of the femoral nerve.The second method uses periarticular infiltration of ropivacaine in combination with an bolus of ropivacaine into an intraarticular catheter placed intraoperatively followed by a continuous intraarticular infusion of ropivacaine. All patient will also receive a sustained-release oral opioid and oral rescue opioids determined by pain severity using the Visual Analog Scale (VAS)

Conditions

• Knee Arthroplasty

Interventions

Type	Name	Description
PROCEDURE	Continuous femoral nerve block + periarticular infiltration	Initial bolus of ropivacaine 5mg/ml 30mls into the femoral-nerve-catheter preoperatively. Periarticular infiltration of ropivacaine 2mg/ml 150 mls intraoperatively. Continuous perineural infusion of ropivacaine 2mg/ml at a rate of 6 mls/hr postoperatively. Rate can be adjusted to achieve optimal pain control and avoid motor blockade.
PROCEDURE	Intraarticular and periarticular ropivacaine	Periarticular infiltration of 150 mls ropivacaine 2mg/ml intraoperatively, intraarticular injection of 40 mls ropivacaine 2 mg/ml at skin closure followed by infusion of ropivacaine 2 mg/ml at a rate of 4 mls/hr delivered by an intraarticular catheter until the morning of postoperative day 3.

Timeline

• Start date: 2010-10-01
• Primary completion: 2015-09-01
• Completion: 2015-10-01
• First posted: 2010-10-21
• Last updated: 2015-04-09

Locations

1 site across 1 country: Austria