NCT01216982

Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders

Effects of Omega-3 EPA/DHA for Soldiers at Risk for Mood Disorders: A Mood Resilience Trial

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 256 (estimated)
• Sponsor: United States Department of Defense · Federal
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

Stress-related disorders are among the most prevalent and expensive medical consequences of participation in military operations. Omega-3 fatty acids EPA/DHA derived from fish oil are known to benefit both neuronal development in the young, and cognition and mood in various populations. It is possible that soldiers receiving Omega-3 EPA/DHA will exhibit significantly higher cognitive performance, better affect/mood state, and less combat stress symptomatology compared to the placebo after 12 weeks of supplementation. A goal would be to reduce the prevalence of combat stress injuries in military personnel.

Conditions

• Mood Disorders
• Depression
• Combat Disorders
• Stress Disorders

Interventions

Type	Name	Description
DRUG	Lovaza, omega-3 fatty acid ethyl ester	Three 1g capsules/day for three months; this corresponds to a total of 2520mg EPA+DHA/day
DRUG	Placebo, visually identical to Lovaza	Three 1g corn oil capsules/day for three months

Timeline

• Start date: 2010-11-01
• Primary completion: 2011-02-01
• Completion: 2011-06-01
• First posted: 2010-10-07
• Last updated: 2011-03-09

Locations

1 site across 1 country: Iraq