NCT01210781

Target Planning for Placement of DBS-electrodes and Follow-up of the Clinical Efficacy of Stimulation

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: University of Zurich · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement. The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires. * Trial with surgical intervention

Detailed description

Deep brain stimulation (DBS) has been established as therapy for severe forms of Parkinson's disease and other indications. A common target for stimulation is the subthalamic nucleus (STN). Nevertheless, there is no agreement on the mechanisms how DBS leads to clinical improvement. The project aims to describe the variability of target coordinates in the patient group and to relate it to clinical outcome as documented in standardized questionaires.

Conditions

• Movement Disorders
• Epilepsy

Interventions

Type	Name	Description
PROCEDURE	deep brain stimulation (DBS)	deep brain stimulation (DBS) is in itself not part of this study but a clinical indication. The study aims at documenting DBS parameters and outcome

Timeline

• Start date: 2009-09-01
• Primary completion: 2025-12-01
• Completion: 2025-12-01
• First posted: 2010-09-28
• Last updated: 2023-12-01

Locations

1 site across 1 country: Switzerland