NCT01209845

Ketamine for Low Mood States in the ER

Low Dose Ketamine for Low Mood States: An Emergency Department Feasibility Study for Depressed Patients

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 14 (actual)
• Sponsor: Yale University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The investigators hope to see if a commonly used drug such as ketamine could help depressed ER patients feel better and improve their mood quickly.

Detailed description

Rapid-onset antidepressants could have important clinical impact if their benefits extended to Emergency Department (ED) patients. We hope to explore the preliminary feasibility, tolerability and efficacy of single-dose, intravenous (IV) ketamine in depressed ED patients who presented with suicide ideation (SI). The manuscript (article) for this study has been retracted because Yale University conducted an investigation that determined that the description of the research was not accurate. The article misrepresents both the protocol-specified doses and the actual delivered doses of ketamine.

Conditions

• Depression
• Suicide Ideation

Interventions

Type	Name	Description
DRUG	ketamine	intravenous ketamine(0.2 mg/kg) over 1-2 minutes IV

Timeline

• Start date: 2010-04-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2010-09-27
• Last updated: 2020-08-24

Locations

1 site across 1 country: United States