NCT01206946

Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants

Effect of Antenatal Steroids for Women at Risk of Late Preterm Delivery on Neonatal Respiratory Morbidity

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 700 (estimated)
• Sponsor: American University of Beirut Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 49 Years
• Healthy volunteers: Not accepted

Summary

The hypothesis of the study is that administration of antenatal steroid to women at high risk of preterm birth after 34 weeks of gestation would reduce the risk of respiratory complications, specifically Respiratory Distress Syndrome (RDS) or Transient Tachypnea of the Newborn (TTN) in late preterm babies.

Conditions

• Respiratory Distress Syndrome, Newborn
• Transient Tachypnea of the Newborn

Interventions

Type	Name	Description
DRUG	Betamethasone	A single course of betamethasone (two doses of 12 mg/dose given at 24 hourly intervals)
OTHER	Normal Saline	Two doses of 2ml of normal saline given at 24 hourly intervals

Timeline

• Start date: 2010-09-01
• Primary completion: 2013-09-01
• Completion: 2013-09-01
• First posted: 2010-09-22
• Last updated: 2011-06-23

Locations

5 sites across 1 country: Lebanon