NCT01182805

Radiofrequency-based Speckle Tracking Echocardiography to Evaluate Diastolic Function

• Status: Completed
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate a novel ultrasound system's ability to assess the relaxing properties of the heart compared to current techniques.

Conditions

• Heart Failure, Diastolic

Interventions

Type	Name	Description
DEVICE	Echocardiography system Ultra DCI Model 5000	Each subject will undergo scanning using the investigational echocardiography system (Ultra DCI Model 5000)to measure Diastolic Circumferential Strain Rate during Isovolumic Relaxation (DCSR-IVR) as novel measure of diastolic function.
DEVICE	Echocardiography machine GE Vivid E9	Each subject will undergo echocardiography using a conventional echocardiography machine to evaluate the early diastolic mitral annular velocity (E-prime) using tissue Doppler as a standard measure of diastolic function.
DEVICE	Diastolic function assessment	Each subject will undergo standard echocardiographic measure of the mitral inflow pattern and invasive catheter-derived measure of left ventricular end-diastolic pressure to determine their diastolic function. This evaluation will be used as the gold standard for this study.

Timeline

• Start date: 2010-08-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2010-08-17
• Last updated: 2023-10-16
• Results posted: 2012-08-03

Locations

1 site across 1 country: United States