NCT01180920

The Importance of Periostin in Periodontal Health and Disease

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 22 (actual)
• Sponsor: University of Michigan · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Accepted

Summary

The goal of this study is to determine the clinical importance of Periostin in oral health and disease. The long-term goal will be to develop practical applications for the diagnosis, treatment, prevention and cure of human periodontal diseases.

Detailed description

It is hypothesized that Periostin levels are decreased during periodontal diseases, thereby, elevating the hosts' susceptibility to periodontal breakdown. The specific aims are the following; To determine if Periostin is a biomarker of periodontal disease, and To evaluate Periostin in periodontal tissue healing and homeostasis by harvesting healthy or diseased tissue from 22 patients requiring periodontal surgery.

Conditions

• Periodontal Disease
• Non-diseased Patients

Timeline

• Start date: 2011-06-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2010-08-12
• Last updated: 2014-12-02

Locations

1 site across 1 country: United States