NCT01169662

Effects of Dietary Nitrate From Vegetable/Fruit Juice on Cerebral Blood Flow Parameters

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Northumbria University · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

Nitrate provides the body with an alternative source of Nitric Oxide which plays a large role in promoting blood flow and reducing blood pressure. Nitrate supplementation with vegetable/fruit juice has recently been shown to reduce blood pressure and reduce energy expenditure during low intensity exercise. Such findings combined with the previously known biological effects of nitric oxide would suggest that nitrate supplementation would also impact on blood flow. The aim of this study is to examine the effects of dietary nitrate supplementation via vegetable/fruit juice drink on cerebral (brain) blood flow (using Near Infrared Spectroscopy).

Conditions

• Cerebrovascular Circulation
• Cognitive Impairment

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Vegetable/fruit juice	450ml active juice, 45ml no added sugar fruit squash (for flavour)
DIETARY_SUPPLEMENT	Placebo juice	50 ml No Added Sugar fruit squash, 45 ml Pressed Apple Juice, 405ml with water.

Timeline

• Start date: 2010-02-01
• Primary completion: 2010-07-01
• Completion: 2010-07-01
• First posted: 2010-07-26
• Last updated: 2010-10-13

Locations

1 site across 1 country: United Kingdom