NCT01164852

Aggressive Versus Expectant Management of Severe Preeclampsia Remote From Term

Expectant Management of Severe Preeclampsia at 28 to 33 Week's Gestation:a Randomized Controlled Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 264 (actual)
• Sponsor: Complejo Hospitalario Dr. Arnulfo Arias Madrid · Academic / Other
• Sex: Female
• Age: —
• Healthy volunteers: Accepted

Summary

How best to manage preeclampsia remote from term is controversial because of conflicting maternal and neonatal risks. Gestational age is the most important determinant of neonatal outcome. There are two basic approaches when delivery is not clear indicated by assessment of maternal and fetal well-being. The interventionist care when the delivery is planned within 48 hours and the expectant care which refers to pregnancy prolongation during which time women and fetuses are carefully monitored for indications for delivery. The purpose of this study is to evaluate maternal and perinatal outcomes with expectant vs interventionist or aggressive management of severe preeclampsia at 28 to 33 weeks of gestation.

Detailed description

Severa Preeclampsia between 28 and 33 weeks of gestation Women and fetus with stable condition All women receive complete dosis of steroids

Conditions

• Preeclampsia

Interventions

Type	Name	Description
PROCEDURE	Delivery	Termination of pregnancy (delivery)after completed corticosteroids

Timeline

• Start date: 2010-08-01
• Primary completion: 2012-08-01
• Completion: 2012-08-01
• First posted: 2010-07-19
• Last updated: 2012-08-14

Locations

8 sites across 6 countries: Ecuador, Guatemala, Mexico, Panama, Peru, Venezuela