NCT01162850

Oral Polypodium Leucotomos for Melasma

A Randomized Double-Blind Placebo Controlled Study Evaluating the Effectiveness and Tolerability of Oral Polypodium Leucotomos in Patients With Melasma

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: University of Miami · Academic / Other
• Sex: Female
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Primary Objective: To determine whether there is improvement in the melasma of participants taking oral Polypodium Leucotomos Secondary Objective: To determine whether oral Polypodium Leucotomos is well tolerated in study subjects with melasma. To determine whether treatment with Polypodium Leucotomos improves the health-related quality of life.

Detailed description

Polypodium Leucotomos is a fern, also known as Calaguala used by the natives of northern Honduras as a treatment against malignant tumors Used in Spain and Central America for the treatment of psoriasis, atopic dermatitis and repigmentation of vitiligo. Oral Polypodium Leucotomos is safe and effective in patients with melasma.

Conditions

• Melasma

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Polypodium Leucotomos	Oral capsule at 240 mg taken twice a day for 12 weeks
DIETARY_SUPPLEMENT	Placebo	240 mg Placebo taken orally twice daily created by company which manufactured active ingredient

Timeline

• Start date: 2008-05-01
• Primary completion: 2009-06-01
• Completion: 2009-06-01
• First posted: 2010-07-15
• Last updated: 2011-08-05

Locations

1 site across 1 country: United States