NCT01154803

Effectiveness of Nutritional Supplementation in Preventing Malnutrition in Children With Infection

Effectiveness of Nutritional Supplementation (RUTF and Multi Micronutrient) in Preventing Malnutrition in Children 6-59 Months With Infection (Malaria, Pneumonia, Diarrhoea), a Randomized Controlled Trial in Nigeria

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,213 (actual)
• Sponsor: Medecins Sans Frontieres, Netherlands · Academic / Other
• Sex: All
• Age: 6 Months – 59 Months
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether 14 days nutritional supplementation with Ready to use therapeutic Food (RUTF) or micronutrients alone to children having an infection will prevent malnutrition and reduce the frequency of morbidity.

Detailed description

Anorexia due to infection might lead to weight loss. In many settings total recovery is problematic what might result in a permanent lower weight. A short period high quality food supplementation could improve weight gain after an infection. A complete high quality food will be tested, but also micronutrients alone as there is no information on what children with an infection exactly need as a supplement. Children aged 6-59 months presenting with diarrhoea, malaria or lower respiratory tract infection (LRTI) are provided for 2 weeks with * RUTF supplement (Plumpynut®) of 500 kcal/day * Multi-micronutrient powder (MNP) * Placebo to MNP The followup period is 6 months. Anthropometric indicators and morbidity are assessed monthly. Participants are invited to attend the study clinic if any signs of disease are noticed.

Conditions

• Malnutrition
• Malaria
• Lower Respiratory Tract Infection
• Diarrhoea

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Ready to Use Therapeutic Food (RUTF)	1 sachet/day, 500 kcal and multi micronutrients (fortified high quality food(RUTF),for 2 weeks after an illness (malaria, diarrhoea, pneumonia)
DIETARY_SUPPLEMENT	Micronutrient Powder (MNP)	2 sachets / day for 14 days after an illness (diarrheoea, malaria, pneumonia)

Timeline

• Start date: 2012-02-01
• Primary completion: 2013-02-01
• Completion: 2013-02-01
• First posted: 2010-07-01
• Last updated: 2013-10-16

Locations

1 site across 1 country: Nigeria