NCT01153139

Long-term Bilateral Theta Burst Stimulation for the Treatment of Major Depression

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: University Hospital Tuebingen · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Repetitive transcranial magnetic stimulation has been shown to be moderately effective in the treatment of major depression. Theta burst stimulation (TBS) is a new form of rTMS that may exert larger effects. This sham-controlled study examines the effectivity of daily bilateral TBS to the dorsolateral frontal cortex over 6 weeks in 2x16 patients with major depression add on to the local standard of a combined pharmacological/psychotherapeutical treatment.

Conditions

• Major Depression

Interventions

Type	Name	Description
DEVICE	Repetitive Transcranial Magnetic Stimulation (Theta Burst Stimulation, TBS)	intermittent TBS (iTBS) to the left DLPFC (600 stimuli, 80% resting motor threshold) continuous TBS (cTBS) to the right DLPFC (600 stimuli, 80% resting motor threshold)

Timeline

• Start date: 2010-04-01
• Primary completion: 2012-12-01
• Completion: 2013-07-01
• First posted: 2010-06-29
• Last updated: 2013-07-16

Locations

1 site across 1 country: Germany