NCT01149278

Assessment of Two Levels of Arterial Pressure on Survival in Patients With Septic Shock

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 800 (actual)
• Sponsor: University Hospital, Angers · Other Government
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The ideal mean arterial pressure in patients with septic shock is unknown. The expert's recommandations have stated a target between 65 and 70 mm Hg. However the scientific basis are weak. Indead there are only few prospective studies which addressed this question without clear answer. Therefore we designed a RCT in order to assess the effect on mortality of two levels of mean arterial pressure in patients with septic shock.(800 patients, 30 centres)

Conditions

• Septic Shock
• Arterial Pressure
• Hemodynamics
• Mortality
• Clinical Trial

Interventions

Type	Name	Description
DRUG	maintain mean arterial pressure between 80-85 mm Hg	protocolized hemodynamic care aiming to maintain mean arterial pressure between 80-85 mm Hg
OTHER	maintain mean arterial pressure between 65-70 mm Hg	protocolized hemodynamic care aiming to maintain mean arterial pressure between 65-70 mm Hg

Timeline

• Start date: 2010-03-01
• Primary completion: 2012-09-01
• Completion: 2012-09-01
• First posted: 2010-06-23
• Last updated: 2012-11-05

Locations

1 site across 1 country: France