Clinical Trials Directory

Trials / Completed

CompletedNCT01143389

Corneal Crosslinking in Patients With Keratoconus and Post-Refractive Ectasia

Evaluation of Two Riboflavin Dosing Regimens for Corneal Collagen Cross-Linking in Eyes With Progressive Keratoconus or Ectasia

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
510 (actual)
Sponsor
Price Vision Group · Industry
Sex
All
Age
10 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to evaluate the effectiveness of using riboflavin and UV light to treat progressive keratoconus or post-refractive corneal ectasia.

Detailed description

The primary objective of this study is to evaluate two riboflavin-dosing regimens for corneal collagen cross-linking to slow the progressive changes in corneal curvature in eyes with progressive keratoconus or post-refractive ectasia.

Conditions

Interventions

TypeNameDescription
DRUGRiboflavinRiboflavin 0.1% eye drops are applied before and during irradiation of the cornea.
DEVICEUVX lightUVX 365 nm wavelength light source is applied with continued application of riboflavin.

Timeline

Start date
2010-05-01
Primary completion
2017-05-30
Completion
2017-08-30
First posted
2010-06-14
Last updated
2018-06-06
Results posted
2018-05-04

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT01143389. Inclusion in this directory is not an endorsement.