NCT01141855

Smoking Termination Opportunity for inPatients

Effectiveness of Inpatient Initiated Varenicline Tartrate for Smoking Cessation, for Smoking Related Illnesses.

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 392 (actual)
• Sponsor: The Queen Elizabeth Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The Smoking Termination Opportunity for inPatients, (STOP) project is designed to capture the opportunity that is provided by admission for acute smoking related illness, to assist patients through withdrawal by use of a combination of: * the new medication Champix with * best practice counselling * initiated in an inpatient setting to achieve: * sustained smoking abstinence * reduced hospital bed and health service utilisation * reduced inpatient smoking and craving prior to discharge

Detailed description

A national standard in public hospitals for the management of smoking in patients admitted with smoking related acute illnesses is lacking. Where such patients have continued to smoke up until the time of admission, it can be assumed that "primary" prevention has failed. Once admitted, there is a vastly under-utilised opportunity, by use of a structured and systematic approach, to intervene with a secondary prevention attempt. This takes advantage of the synergy of: 1. the smoker is a "captive audience" and may be receptive to considering lifestyle factors that have lead to the admission, and 2. best practice medication and counselling can be initiated prior to discharge. If proven to be cost-effective in our analysis, a systematic roll-out of this secondary prevention initiative would be advocated. ie translation of research into practice.

Conditions

• Tobacco Use Disorder

Interventions

Type	Name	Description
DRUG	Champix	Standard MIMS dosage (including period of titration) will be used. 0.5mg daily for 3 days 0.5mg b.d. for 4 days 1mb b.d. for 70 days (full course 3 months)
BEHAVIORAL	Counselling alone	Quit SA 5A counselling over the phone. Maximum 8 calls over a 3 month period

Timeline

• Start date: 2008-05-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2010-06-11
• Last updated: 2012-08-08

Locations

3 sites across 1 country: Australia