NCT01138020

Cognitive Rehabilitation of Blast Traumatic Brain Injury (TBI)

Cognitive Rehabilitation of Blast-induced Traumatic Brain Injury

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 77 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 21 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the efficacy of a structured rehabilitation program on cognitive function and quality of life in individuals with blast-induced traumatic brain injury (bTBI).

Detailed description

The most common impairments following blast-induced traumatic brain injury (bTBI) are cognitive deficits in the domain of executive functioning, learning and memory, and functional and psychosocial disabilities that are closely related to these cognitive deficits. There are no treatment protocols available to address the multiple cognitive impairments in bTBI, but cognitive rehabilitation has proven efficacious in the treatment of non-blast TBI. The cognitive training modules the investigators plan to evaluate have improved organization and memory function in patients with non-blast TBI, but it is unknown whether their efficacy exceeds that of programs that focus only on education and support. This study is a between group comparison of a cognitive rehabilitation treatment designed specifically to address the most common cognitive complaints in executive and memory function, and an active control group receiving educational intervention geared at personal management of TBI-related symptoms.

Conditions

• Traumatic Brain Injury
• Cognitive Symptoms

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive Intervention	Cognitive rehabilitation treatment designed specifically to address the most common cognitive complaints in executive and memory function
BEHAVIORAL	Educational intervention	Educational intervention is geared at personal management of TBI-related symptoms.

Timeline

• Start date: 2011-03-01
• Primary completion: 2025-06-30
• Completion: 2025-06-30
• First posted: 2010-06-07
• Last updated: 2026-04-15

Locations

1 site across 1 country: United States