NCT01129713

Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in GERD Patients With Severe EE.

Comparison of Nexium Versus Secretol in the Healing and Controlling of Symptoms in Gastroesophageal Reflux Disease(GERD)Patients With Severe Erosive Esophagitis(EE).

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Effexus Pharmaceutical · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

To compare the complete healing of erosive esophagitis(EE) after 3 weeks of treatment with Secretol 80/80 versus Nexium 40 mg daily.

Detailed description

We hypothesize that Secretol 80/80 daily will demonstrate better efficacy than Nexium 40 mg daily in healing erosive esophagitis(EE)and controlling gastroesophageal reflux disease(GERD)related symptoms after 3 weeks of treatment.In addition, Secretol 80/80 daily will have a faster effect on the aforementioned clinical parameters but a similar safety profile.

Conditions

• Gastroesophageal Reflux Disease (GERD)
• Heartburn
• Indigestion

Interventions

Type	Name	Description
DRUG	Secretol	Comparing 80/80 once daily to Nexium once daily in healing erosive esophagitis.
DRUG	Nexium	Comparing 40 mg Nexium once daily to 80/80 Secretol once daily in healing erosive esophagitis.

Timeline

• Start date: 2010-05-01
• Primary completion: 2015-05-01
• Completion: 2015-05-01
• First posted: 2010-05-25
• Last updated: 2014-08-05

Locations

1 site across 1 country: United States