Clinical Trials Directory

Trials / Completed

CompletedNCT01111890

Comparison of the Efficacy of AZARGA® Versus COSOPT® in Patients With Open-Angled Glaucoma or Ocular Hypertension

Status
Completed
Phase
Phase 4
Study type
Interventional
Enrollment
70 (actual)
Sponsor
Alcon Research · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Subjects are dosed twice daily at 9AM and 9PM for 12 weeks. The primary efficacy variable is the mean change in Intraocular Pressure (IOP) from baseline to 12 weeks. Secondary efficacy variable: % IOP ≤ 18 millimeters mercury (mmHg). Exploratory endpoint: Ocular discomfort scale after first dose.

Conditions

Interventions

TypeNameDescription
DRUGAzarga (brinzolamide 1% / timolol 0.5%)Dosed twice daily at 9:00 AM and 9:00 PM for 12 weeks
DRUGCosopt (dorzolamide 2% / timolol 0.5%)Dosed twice daily at 9:00 AM and 9:00 PM for 12 weeks

Timeline

Start date
2010-04-01
Primary completion
2011-07-01
Completion
2011-07-01
First posted
2010-04-28
Last updated
2015-07-29

Locations

1 site across 1 country: Canada

Source: ClinicalTrials.gov record NCT01111890. Inclusion in this directory is not an endorsement.