NCT01111045

Dose Finding Study of Bone Morphogenetic Protein 7 (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

A Phase 2, Double Blind, Randomized, Placebo-Controlled, Proof of Concept, Dose Finding Study of Intraarticular Bone Morphogenetic Protein (BMP-7) in Subjects With Osteoarthritis (OA) of the Knee

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 355 (actual)
• Sponsor: Stryker Biotech · Industry
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

The objectives of the study are to evaluate the safety and efficacy of intraarticular BMP-7 for the treatment of osteoarthritis of the knee.

Conditions

• Osteoarthritis of the Knee

Interventions

Type	Name	Description
DRUG	Bone morphogenetic protein 7	Comparison of different doses of the drug via single intraarticular knee injection
DRUG	Placebo	Placebo

Timeline

• Start date: 2010-04-01
• Primary completion: 2011-08-01
• Completion: 2011-08-01
• First posted: 2010-04-27
• Last updated: 2012-02-01

Locations

25 sites across 1 country: United States