NCT01108146

Hydrocortisone in the Treatment of Intrusions in Patients With Posttraumatic Stress Disorder

Monocentric, Double-blind Placebo-Controlled, Randomized Cross-Sectional Clinical Trial of Hydrocortisone (10 and 30 mg/d) in Outpatients With Posttraumatic-Stress-Disorder (PTSD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: Central Institute of Mental Health, Mannheim · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

To test overall efficacy of hydrocortisone on reexperience of traumatic memories (intrusions) and overall symptomatology in patients meeting criteria of complex chronic PTSD.

Conditions

• Posttraumatic Stress Disorder

Interventions

Type	Name	Description
DRUG	Arm 1 Hydrocortisone 10 mg	Group 1: Administration of Hydrocortisone and/or Placebo in the following order: 1 week placebo- 1 week 10 mg hydrocortisone - 1 week placebo - 1 week 30 mg hydrocortisone
DRUG	Arm 2 Hydrocortisone 30 mg	Drug: Hydrocortisone 30 mg Group 2: Administration of Hydrocortisone and/or Placebo in the following order: 1 week hydrocortisone 30 mg/d- 1 week placebo - 1 week hydrocortisone 10 mg/d - 1 week placebo

Timeline

• Start date: 2008-10-01
• Primary completion: 2012-10-01
• Completion: 2012-10-01
• First posted: 2010-04-21
• Last updated: 2018-11-21

Locations

1 site across 1 country: Germany