Trials / Completed
CompletedNCT01090375
Regulation of Intraarticular and Synovium-related Biomarkers of Osteoarthritis. Effect of Acute Mechanical Joint Loading
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- —
- Sponsor
- Bispebjerg Hospital · Academic / Other
- Sex
- Female
- Age
- 55 Years – 75 Years
- Healthy volunteers
- —
Summary
In the present study the microdialysis method is used to investigate biochemical changes within and around the joint simultaneously in both the resting state and in a joint that had been subjected to exercise. The aim of the present study was, by applying the microdialysis technique, to monitor markers of cartilage breakdown and inflammation in 2 different positions of the knee (inside and in the inner part of the knee capsule) in a group of human females with knee osteoarthritis over a period of 3 hours.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Exercise | |
| OTHER | Non Exercise |
Timeline
- Start date
- 2008-08-01
- Primary completion
- 2009-03-01
- First posted
- 2010-03-19
- Last updated
- 2010-03-19
Source: ClinicalTrials.gov record NCT01090375. Inclusion in this directory is not an endorsement.