NCT01084187

Correlation Study of Vascular Parameters in Hypertensive Men With Erectile Dysfunction

Correlation of Flow Mediated Dilation of Brachial Artery and Carotid Intima Media Thickness With Erectile Dysfunction Severity and Clinical Response to PDE 5 Inhibitor in Hypertensive Men

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Hospital Universitario Pedro Ernesto · Academic / Other
• Sex: Male
• Age: 50 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to assess the correlation of FMD of brachial artery and carotid intima media thickness with ED severity and clinical response to vardenafil in hypertensive men.

Detailed description

To achieve this objective, a prospective study will be conducted, with hypertensive patients ranging from 50 to 70 years, presenting vasculogenic erectile dysfunction for over six months and sexually actives. All patients will be assessed for clinical and laboratorial data, endothelial dysfunction, endothelium independent vasodilation and carotid intima media thickness at the inclusion of the study. They will receive medical orientations from the same urologist and will return after four attempts with 20 mg of vardenafil.

Conditions

• Erectile Dysfunction
• Arterial Hypertension
• Endothelial Dysfunction

Interventions

Type	Name	Description
DRUG	Vardenafil	vardenafil 20 mg on demand or vardenafil daily or placebo

Timeline

• Start date: 2010-01-01
• Primary completion: 2010-12-01
• Completion: 2011-02-01
• First posted: 2010-03-10
• Last updated: 2011-04-18

Locations

1 site across 1 country: Brazil