Clinical Trials Directory

Trials / Terminated

TerminatedNCT01077297

Tezosentan in Pulmonary Arterial Hypertension

Multicenter, Open-label, Non-comparative, Proof-of-concept, Phase 2a Study to Evaluate the Effect of a Single Infusion of Tezosentan on Pulmonary Vascular Resistance in Patients With Stable, Chronic Pulmonary Arterial Hypertension, Currently Not Treated With Endothelin Receptor Antagonists, Phosphodiesterase-5 Inhibitors or Prostacyclines

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
3 (actual)
Sponsor
Idorsia Pharmaceuticals Ltd. · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Multicenter, Open-label, Non-comparative, Proof-of-concept, Phase 2a Study to Evaluate the Effect of a Single Infusion of Tezosentan on Pulmonary Vascular Resistance in Patients With Stable, Chronic Pulmonary Arterial Hypertension, Currently Not Treated With Endothelin Receptor Antagonists, Phosphodiesterase-5 Inhibitors or Prostacyclines

Conditions

Interventions

TypeNameDescription
DRUGTezosentansingle infusion of tezosentan 5mg/h over 30 min corresponding to 2.5 mg

Timeline

Start date
2010-08-01
Primary completion
2010-11-01
Completion
2011-09-01
First posted
2010-03-01
Last updated
2018-07-09

Locations

5 sites across 3 countries: United States, France, Switzerland

Source: ClinicalTrials.gov record NCT01077297. Inclusion in this directory is not an endorsement.