NCT01075334

Is a Carnitine Based Food Supplement (PorimoreTM) for Infertile Men Superior to Folate and Zinc With Regard to Pregnancy Rates in Intrauterine Insemination Cycles?

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Shaare Zedek Medical Center · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Many cases of male infertility are poorly understood and regarded as unexplained. Therefore, a etiological treatment for this condition can not be offered in most cases. A beneficial effect on sperm motility was found in trails using antioxidants such as carnitine, zinc and folic acid. However, most studies lacked a sufficient power to detect a significant effect on pregnancy rates. In this study, infertile men with abnormal sperm quality parameters will be randomized to receive either carnitine-based food supplement (Porimore) or folate and Zinc Tablets.

Conditions

• Male Infertility

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Porimore - A Carnitine based food supplement	A daily dose of 2 grams L-carnitine, 1 gr acetyl L-carnitine, 500mg Vitamin C, 400 IU vitamin E, 60 mg Q10, 30mg Zinc Picolinate, 500mcg Folic Acid, 200 Mcg Selenium, 100 MCG Vitamin B12.
DIETARY_SUPPLEMENT	Zinc and Folate Supplementation	500 Mcg Folic acid, 30-60 mg Zinc tablets/ day

Timeline

• Start date: 2010-02-01
• Primary completion: 2010-02-01
• Completion: 2012-12-01
• First posted: 2010-02-25
• Last updated: 2010-02-25

Locations

1 site across 1 country: Israel