Clinical Trials Directory

Trials / Completed

CompletedNCT01059435

A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women

A Randomized, Double-blind, Placebo-controlled, Ascending Single-dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 785 in Healthy Men and Postmenopausal Women

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
74 (actual)
Sponsor
Amgen · Industry
Sex
All
Age
45 Years – 59 Years
Healthy volunteers
Accepted

Summary

The primary objective of this study is to assess the safety and tolerability of romosozumab following single dose subcutaneous (SC) or intravenous (IV) administration in healthy men and postmenopausal women.

Conditions

Interventions

TypeNameDescription
DRUGRomosozumabAdministered subcutaneously or intravenously
DRUGPlaceboAdministered subcutaneously or intravenously

Timeline

Start date
2006-12-13
Primary completion
2007-07-06
Completion
2007-07-06
First posted
2010-02-01
Last updated
2019-07-05
Results posted
2019-07-05

Source: ClinicalTrials.gov record NCT01059435. Inclusion in this directory is not an endorsement.

A First-in-human Study Evaluating Romosozumab (AMG 785) in Healthy Men and Postmenopausal Women (NCT01059435) · Clinical Trials Directory