Clinical Trials Directory

Trials / Completed

CompletedNCT01052506

BIIB033 Single Ascending Dose Study in Healthy Volunteer Subjects

A Randomized, Blinded, Placebo-Controlled, Single Ascending Dose Study of the Safety, Tolerability, and Pharmacokinetics of BIIB033 in Healthy Adult Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
72 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
25 Years – 55 Years
Healthy volunteers
Accepted

Summary

The primary objective of the study is to evaluate the safety and tolerability of single dose of BIIB033 administered to healthy adult volunteers.

Detailed description

BIIB033 is an investigational product being developed to promote remyelination in subjects with multiple sclerosis (MS). This healthy volunteer study will evaluate safety and tolerability of a single dose of BIIB033.

Conditions

Interventions

TypeNameDescription
DRUGBIIB033Single, escalating doses of BIIB033 (8 cohorts IV, 1 cohort SC)
DRUGPlaceboSingle dose of placebo comparator (8 cohorts IV, 1 cohort SC)

Timeline

Start date
2010-01-01
Primary completion
2011-10-01
Completion
2011-10-01
First posted
2010-01-20
Last updated
2017-01-09

Locations

2 sites across 2 countries: United States, Netherlands

Source: ClinicalTrials.gov record NCT01052506. Inclusion in this directory is not an endorsement.