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Trials / Completed

CompletedNCT01004081

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding

Phase 2a, Open-Label, Randomized, Noncomparative Study of BIIB021 in Combination With Exemestane in Women With Hormone Receptor-Positive, Advanced Metastatic Breast Cancer Who Have Progressed on a Nonsteroidal Aromatase Inhibitor

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
54 (actual)
Sponsor
Biogen · Industry
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to assess the efficacy, safety and tolerability of 2 dosing regimens of BIIB021 in combination with exemestane in women whose HR+ breast cancer had progressed following treatment with a nonsteroidal aromatase inhibitor (AI).

Conditions

Interventions

TypeNameDescription
DRUGBIIB021BID orally for 28 days
DRUGBIIB021TIW orally for 28 days
DRUGexemestane (Aromasin)Daily in tablet form for 28 days

Timeline

Start date
2009-11-01
Primary completion
2011-10-01
Completion
2011-10-01
First posted
2009-10-29
Last updated
2015-10-02

Locations

34 sites across 4 countries: United States, Australia, Belgium, Russia

Source: ClinicalTrials.gov record NCT01004081. Inclusion in this directory is not an endorsement.

Hormone Receptor Positive Metastatic Breast Cancer (HR+ mBC) BIIB021 Plus Aromasin Schedule Finding (NCT01004081) · Clinical Trials Directory