NCT01001559

Combination Deplin® and Antidepressant Therapy for a Major Depressive Episode (MDE)- a Retrospective Analysis

Combination Deplin® and Antidepressant Therapy Compared to Antidepressant Therapy Alone for an Episode of Major Depression- a Retrospective Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 242 (actual)
• Sponsor: Pamlab, Inc. · Industry
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

This is a retrospective chart review study to determine if Deplin® 7.5mg-15mg combined with an antidepressant is better than an antidepressant alone in adults with major depression.

Conditions

• Major Depressive Disorder

Interventions

Type	Name	Description
DRUG	L-methylfolate	Subjects must have been on their respective therapies for a minimum of 60 days. L-methylfolate dosing was 7.5 mg or 15 mg daily
DRUG	Selective serotonin reuptake inhibitor (SSRI)	Subject must have been on their respective therapy for a minimum of 60 days. Because this was an observational retrospective analysis, dosing of SSRI/SNRI varied on a per patient basis.
DRUG	Serotonin and norepinephrine reuptake inhibitor (SNRI)	Subject must have been on their respective therapy for a minimum of 60 days. Because this was an observational retrospective analysis, dosing of SSRI/SNRI varied on a per patient basis.

Timeline

• Start date: 2009-08-01
• Primary completion: 2010-12-01
• Completion: 2011-06-01
• First posted: 2009-10-26
• Last updated: 2013-12-19
• Results posted: 2013-12-19

Locations

1 site across 1 country: United States