Clinical Trials Directory

Trials / Unknown

UnknownNCT01000220

Evaluation of Omeprazole Effect on Glaucoma

Status
Unknown
Phase
Phase 1
Study type
Interventional
Enrollment
Sponsor
Shahid Beheshti University of Medical Sciences · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

Omeprazole is a safe drug listed in OTC drug due to its safety. It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users. The effect will be finally assessed.

Detailed description

Omeprazole is a safe drug listed in OTC drug due to its safety. It acts by irreversible inhibition of K/H ATP ase pump and also Na/K ATP ase, Na/H ATP ase.Considering these actions the effect of omeprazole on decreasing intra ocular pressure is an issue of debate.In this Randomized Clinical Trial conducted in labafinejad hospital, patients with glaucoma who need to take omeprazole due to GI problem are evaluated in two groups including placebo and drug users. The effect will be finally assessed.

Conditions

Interventions

TypeNameDescription
DRUGOmeprazole
DRUGPlacebo

Timeline

First posted
2009-10-22
Last updated
2010-05-04

Locations

1 site across 1 country: Iran

Source: ClinicalTrials.gov record NCT01000220. Inclusion in this directory is not an endorsement.