NCT00998569

Neurocognitive Enhancement in Major Depressive Disorder

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: Queen's University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to examine the effects of neurocognitive enhancement on cognitive abilities and related social and adaptive behaviours in individuals diagnosed with major depressive disorder. Subjects in this study will be randomized to receive Neurocognitive Enhancement Therapy (NET) or to a wait list and then NET . Secondary aims include examining whether the cognitive benefits are potentiated by repeated exposure during in-home practice with complementary exercises. Additionally, the investigators will examine the durability of the effects and their generalization to functional capacity and everyday functional performance after completion of the groups.

Conditions

• Major Depressive Disorder

Interventions

Type	Name	Description
BEHAVIORAL	Neurocognitive Enhancement	Neurocognitive Enhancement Therapy (NET) uses behavioural treatment strategies that are designed to improve a range of cognitive skills. NET uses strategies such as coaching, repetition, practice, teaching, group discussion, and compensation for deficits by using cognitive strengths.
BEHAVIORAL	Wait List	Participants will be wait listed for 10 weeks, following which time they will receive the intervention previously described.

Timeline

• Start date: 2009-10-01
• Primary completion: 2012-03-01
• Completion: 2012-03-01
• First posted: 2009-10-20
• Last updated: 2015-08-31

Locations

1 site across 1 country: Canada