NCT00998244

Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux Disease

A Randomized, Double-Blind Crossover Study to Evaluate the Effect of a Very Low Carbohydrate Diet on Gastroesophageal Reflux Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: University of North Carolina, Chapel Hill · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research study is to learn if a very low carbohydrate (sugar) diet or traditional low fat diet is able to reduce symptoms related to gastroesophageal reflux disease (GERD) in people who are overweight. Patients with GERD may experience all or some of the following symptoms: stomach acid or partially digested food re-entering the esophagus (which is sometimes referred to as heartburn or regurgitation) and belching. In this study, the investigators also hope to find out if acid in the esophagus is reduced more by a low carbohydrate diet than a low fat diet.

Conditions

• Gastroesophageal Reflux Disease
• Overweight
• Acid Reflux Disease

Interventions

Type	Name	Description
OTHER	Diet - very low carb or low fat	Diet comparison in Gastroesophageal Reflux Disease

Timeline

• Start date: 2009-09-01
• Primary completion: 2011-12-01
• Completion: 2011-12-01
• First posted: 2009-10-20
• Last updated: 2012-01-09

Locations

1 site across 1 country: United States