NCT00997113

Stress During Deep Sedation With Propofol With and Without Alfentanil

Physiologic Stress During Procedural Sedation With and Without Alfentanil

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Hennepin Healthcare Research Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized clinical trial of deep procedural sedation with propofol with and without supplemental alfentanil. Patients will be assessed for total and fractionated serum catecholamines before and after the procedure in addition to usual procedural sedation outcomes parameters to assess the adrenergic effect of propofol sedation without supplemental opioid.

Conditions

• Sedation

Interventions

Type	Name	Description
DRUG	propofol	1 mg/kg IV followed by 0.5 mg/kg iv prn sedation
DRUG	alfentanil	alfentanil 10 ug/kg immediately prior to propofol dose

Timeline

• Start date: 2009-10-01
• Primary completion: 2012-10-01
• Completion: 2012-12-01
• First posted: 2009-10-19
• Last updated: 2014-09-25
• Results posted: 2014-09-25

Locations

1 site across 1 country: United States