NCT00996710

Genomic Structural Variation in Cancer Susceptibility

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,275 (actual)
• Sponsor: Memorial Sloan Kettering Cancer Center · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Accepted

Summary

This study will look for new types of gene changes that may be related to cancer in some patients. Some gene changes (mutations) are passed on from parents to offspring (child). Other gene changes are new and are seen for the first time in a child. They are not seen in the parent. Some of these gene changes may cause cancers in the offspring. We will look for gene changes by studying patients with cancer their parents and family members without cancer. In this study, we will be able to find gene changes that occur in the cancer patient but not in the rest of the family. Knowing the role that new gene changes play in cancer risk may help us find people at a higher risk of getting cancer.

Conditions

• Breast Cancer
• Colon Cancer
• Germ Cell Cancer
• Neuroblastoma
• Rectal Cancer
• Sarcoma

Timeline

• Start date: 2009-10-01
• Primary completion: 2026-10-01
• Completion: 2026-10-01
• First posted: 2009-10-16
• Last updated: 2025-11-04

Locations

1 site across 1 country: United States