NCT00984308

Diagnosis and Treatment of Sleep Apnea in Cerebrovascular Disease

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 225 (actual)
• Sponsor: VA Office of Research and Development · Federal
• Sex: All
• Age: 40 Years
• Healthy volunteers: Not accepted

Summary

Sleep apnea is common among Veterans with cerebrovascular disease (stroke or transient ischemic attack \[TIA\]), leads to hypertension, and is associated with recurrent stroke and death. Although continuous positive airway pressure (CPAP) safely treats sleep apnea, few Veterans with cerebrovascular disease are diagnosed with sleep apnea or offered treatment.

Detailed description

The project sought to evaluate whether a diagnostic and therapeutic intervention strategy among Veterans with cerebrovascular disease and hypertension using unattended polysomnography and auto-titrating CPAP with a targeted adherence evaluation and educational protocol resulted in: an improved rate of diagnosed sleep apnea, an improved rate of treated sleep apnea, and improved blood pressure control.

Conditions

• Obstructive Sleep Apnea
• Stroke
• Transient Ischemic Attack
• Hypertension

Interventions

Type	Name	Description
PROCEDURE	CPAP Therapy for Newly Diagnosed Obstructive Sleep Apnea (OSA)	Continuous Positive Airway Pressure (CPAP) is provided for those patients who are diagnosed with OSA.

Timeline

• Start date: 2008-12-23
• Primary completion: 2011-09-30
• Completion: 2011-09-30
• First posted: 2009-09-25
• Last updated: 2017-06-14
• Results posted: 2015-09-01

Locations

2 sites across 1 country: United States