NCT00960830

Mirtazapine Reduces ICD Shocks in ICD Patients With Depression and Anxiety

Mirtazapine Reduces ICD Appropriate Shocks in Cardioverter Implanted Patients With Depression and Anxiety

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: Universidad Nacional de Rosario · Academic / Other
• Sex: All
• Age: 65 Years – 87 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate if the use of antidepressant medication in depressed patients with implantable cardioverter defibrillator reduces the number of ICD's shocks as it improves depressive affect.

Detailed description

episodes of arrhythmia remain present even after icd implantation, this is specially true in depressed patients. it is hypothesized that improving mood state by means of an antidepressant drug . namely mirtazapine. could be responsible of alleviating the number of appropriate shocks delivered by the cardioverter. this could be due to a direct effect of the drug itself or an indirect effect of improving anxious and depressive affect. the mood and anxiety state are measured with the HADS scale

Conditions

• Depression
• Anxiety

Interventions

Type	Name	Description
DRUG	mirtazapine	mirtazapine 15 mg daily tablets
DRUG	mirtazapine	15 mg daily

Timeline

• Start date: 2007-04-01
• Primary completion: 2008-04-01
• Completion: 2008-11-01
• First posted: 2009-08-18
• Last updated: 2009-08-18

Locations

1 site across 1 country: Argentina