NCT00946530

Light Treatment for Sleep/Wake Disturbances in Alzheimer's Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 118 (actual)
• Sponsor: Stanford University · Academic / Other
• Sex: All
• Age: 55 Years – 100 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to demonstrate the efficacy of timed exposure to bright light for the treatment of disturbed nighttime sleep and daytime wake in community-dwelling dementia patients and their caregivers, and to determine if there are genetic relationships between memory problems and sleep problems

Detailed description

1. Efficacy: Up to 4 weeks of morning bright light exposure will be more efficacious than morning dim light in consolidating nighttime sleep as assessed by actigraphy. 2. Predictors of response: We expect the primary predictor of treatment response will be initial MMSE score. Secondary predictors include baseline sleep/wake and circadian parameters and age. 3. Effectiveness: Bright light treatment will be more effective than dim light in improving quality of life. 4. An understanding of some of the genetic markers of memory and/or sleep problems.

Conditions

• Sleep Initiation and Maintenance Disorders

Interventions

Type	Name	Description
DEVICE	Bright light	Participants uses bright light
DEVICE	Control	Participants uses dim light

Timeline

• Start date: 2004-09-01
• Primary completion: 2010-12-01
• Completion: 2010-12-01
• First posted: 2009-07-27
• Last updated: 2018-10-03
• Results posted: 2017-03-29

Locations

1 site across 1 country: United States