NCT00946127

ETV Versus Shunt Surgery in Normal Pressure Hydrocephalus

Endoscopic Third Ventriculostomy (ETV) Versus Ventriculoperitoneal Shunting (VPS) for the Surgical Management of Normal Pressure Hydrocephalus

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 13 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to test and compare the efficacy of Endoscopic Third Ventriculostomy with shunting of Cerebrospinal fluid (CSF)for treatment for patients of Normal pressure Hydrocephalus.

Detailed description

Normal pressure Hydrocephalus is a reversible disorder of cognition and gait disorder.Currently the shunting of CSF is the recommended treatment of these patients. Even though shunts are known to be beneficial treatment of Hydrocephalus they often need treatment or revision for infection or malfunction. Endoscopic Third Ventriculostomy is a treatment without complications of shunt and is known to benefit obstructive forms of hydrocephalus.Few studies have also shown that it may be efficacious treatment Normal pressure Hydrocephalus.

Conditions

• Hydrocephalus

Interventions

Type	Name	Description
PROCEDURE	Ventriculoperitoneal Shunt Placement	In the subjects who choose this arm, at the start of study- CSF (Cerebrospinal fluid ) will be shunted to peritoneum by placing a ventriculoperitoneal shunt catheter with or without shunt valves or anti-siphon device.
PROCEDURE	Endoscopic Third Ventriculostomy(ETV)	Patients who choose to undergo ETV arm would undergo a ventriculostomy at the start of study.

Timeline

• Start date: 2009-03-01
• Primary completion: 2011-10-01
• Completion: 2011-10-01
• First posted: 2009-07-24
• Last updated: 2012-10-03

Locations

1 site across 1 country: United States