Clinical Trials Directory

Trials / Completed

CompletedNCT00941681

Pharmacokinetics of Oral CK-1827452 in Patients With Stable Heart Failure

An Open Label Study to Investigate the Pharmacokinetics of CK-1827452 Administered Orally to Patients With Stable Heart Failure

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
35 (actual)
Sponsor
Cytokinetics · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is designed to understand the pharmacokinetics of different oral formulations of CK-1827452 being considered for future studies in patients with heart failure. This study will compare the pharmacokinetics and safety and tolerability of both modified-release (MR) and immediate-release (IR) oral formulations of CK-1827452.

Conditions

Interventions

TypeNameDescription
DRUGCK-182745250 mg MR CK-1827452 BID for 10 days
DRUGCK-182745237.5 mg IR CK-1827452 TID for 10 days
DRUGCK-1827452100 mg MR CK-1827452 BID for 10 days

Timeline

Start date
2009-04-01
Primary completion
2009-10-01
Completion
2009-10-01
First posted
2009-07-17
Last updated
2013-02-12
Results posted
2010-12-21

Locations

3 sites across 1 country: Georgia

Source: ClinicalTrials.gov record NCT00941681. Inclusion in this directory is not an endorsement.