Clinical Trials Directory

Trials / Terminated

TerminatedNCT00940615

The Effect of Aerobic Exercise on Mild Traumatic Brain Injury

Aerobic Exercise in TBI: White Matter Integrity and Cognition

Status
Terminated
Phase
N/A
Study type
Interventional
Enrollment
24 (estimated)
Sponsor
US Department of Veterans Affairs · Federal
Sex
All
Age
18 Years – 50 Years
Healthy volunteers
Not accepted

Summary

The current project will examine the effects of aerobic exercise on cognition among a group of veterans who have suffered a mild traumatic brain injury.

Detailed description

There is substantial evidence that a large number of individuals who experience TBI will demonstrate life-long deficits in cognitive or social functions. An estimated 80-90,000 Americans with TBI suffer life-long impairment of physical, cognitive, and psychosocial skills to the degree that they are unable to return to school or work. Research on rehabilitation for mTBI has been minimal and typically has focused on speech, pain management, dizziness, fatigue, irritability, and sensory disorders. The results of the few studies that have examined long-term cognitive effects of mTBI have offered conflicting results. The current research will investigate the efficacy of an aerobic exercise intervention among individuals with mild traumatic brain injury (mTBI). This project will examine changes in fractional anisotropy (FA) values and cognitive functioning among individuals diagnosed with mTBI in a monitored aerobic exercise regimen, versus a low impact stretching and toning control group.

Conditions

Interventions

TypeNameDescription
OTHERaerobic exercise, participants assigned to the exercise treatment group of the proposed study will participate in an aerobic exercise regimen of brisk walking on a treadmill for a 60 minute interval, three times a week
OTHERstretching/toningIndividuals in the control group will participate in a low intensity stretching and toning session for 60 minutes, three times a week

Timeline

Start date
2009-09-01
Primary completion
2010-09-01
Completion
2010-09-01
First posted
2009-07-16
Last updated
2015-06-26

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00940615. Inclusion in this directory is not an endorsement.